BDBM388971 N-[4-(7-(4-cyanophenyl)-5-{[(3R)-1- methylpiperidin-3- yl]methoxy}imidazo[1,2- c]pyrimidin-8-yl)-2-fluorobenzyl]- N,N',N'-trimethylurea::US10800779, Example 85::US11401272, Example 85::US9944647, Example 85
SMILES CN(C)C(=O)N(C)Cc1ccc(cc1F)-c1c(nc(OC[C@@H]2CCCN(C)C2)n2ccnc12)-c1ccc(cc1)C#N
InChI Key InChIKey=BCWQYIXFXNHFQR-JOCHJYFZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 388971
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair